Cyclooxygenase in biology and disease
نویسندگان
چکیده
منابع مشابه
Cyclooxygenase in biology and disease.
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the past decade, however, more progress has been made in understanding the role of cyclooxygenase enzymes in biology and disease than at a...
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Cyclooxygenase (COX), also known as prostaglandin endoperoxide synthase, is the key enzyme required for the conversion of arachidonic acid to prostaglandins. Two COX isoforms have been identifi ed, COX-1 and COX-2. Generally, the COX-1 enzyme is produced constitutively (e.g. in gastric mucosa), whereas COX-2 is highly inducible (e.g. at sites of infl ammation and cancer). Traditional non-steroi...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 1998
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.12.12.1063